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From Surgery Antiseptic to Modern Mouthwash

Ever wondered where LISTERINE® rinse got its name? Dr. Joseph Lawrence, the creator of LISTERINE® mouthwash, wanted to name his work after a scientist who paved the way. Dr. Joseph Lister, an English doctor and surgeon, became the first surgeon to perform an operation in a chamber sterilized with pulverized antiseptic. The result? More patients survived than ever before. Inspired, Lawrence created a unique formulation of his own that was perfect for killing germs in tissues, like those found in your mouth.

*NOT ALL PRODUCTS ARE COMMERCIALLY AVAILABLE IN SINGAPORE.

From Surgery Antiseptic to Modern Mouthwash

1860

1860

Louis Pasteur’s theory that invisible germs are the cause of numerous infections inspires an English doctor named Joseph Lister.


1865

Lister becomes the first surgeon to perform an operation in a chamber sterilized by pulverizing antiseptic in the air. Mortality rates begin to fall.


1876

Lister publicly recognizes the work of 2 men working to modernize surgical practices: Dr. Joseph Lawrence and Robert Wood Johnson, founder of Johnson & Johnson.


1879

1879

Inspired by Lister, Lawrence creates LISTERINE® mouthwash, a unique antiseptic for use in surgeries and bathing wounds.

1881

Lambert Pharmaceutical Co. buys the rights to the LISTERINE® formula and begins to produce and market it.


1895

Studies show that LISTERINE® rinse is effective at killing germs in the mouth, and it catches the attention of dentists.

1914

LISTERINE® mouthwash becomes the first prescription product in the United States to also be sold over the counter and is marketed as an oral germ killer.


1920s

LISTERINE® mouthwash renames bad breath “halitosis” and sales rise.


1997

LISTERINE® mouthwash puts the tooth fairy out of a job in an iconic commercial.


2006

LISTERINE® mouthwash makes a bold statement: rinsing with LISTERINE® mouthwash reduces plaque by up to 52% more than brushing alone.


2008

LISTERINE SMART RINSE® and LISTERINE® HEALTHY WHITE™ VIBRANT launch in the U.S. market.


2009-2011

2009 - 2011

LISTERINE® rinse launches the TOTAL CARE line in the US market.

2012

2012

LISTERINE® rinse releases ULTRACLEAN® line to replace the ADVANCED mouthwash line.

2012b

2012

LISTERINE® rinse launches Fluoride Defense to replace LISTERINE® RESTORING.

2014

2014

LISTERINE® mouthwash launches floss and NATURALS line in the U.S. market.

Get Your Mouth 100% Clean
Get Your Mouth 100% Clean

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Why LISTERINE®?
Why LISTERINE®?

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LISTERINE® vs Germs
LISTERINE® vs Germs

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Date Last Modified: July 02, 2026

Disclaimer: Advice on oral care provided on this site is not intended as a substitute for professional medical/dental advice, diagnosis, or treatment.

Always seek the advice of your physician, dental professional, or other qualified health provider with any questions you may have regarding a medical/dental condition.